个人简介

周明兵，男，1975年10月出生，教授，浙江省151人才工程第三层次，浙江省中青年学科带头人。

研究方向

竹子生长发育表观遗传学，竹子快速生长机理

学习与工作经历

2000年9月-2003年7月：贵州大学攻读硕士学位

2006年9月-2010年11月：上海交通大学攻读博士学位

2009年9月-2010年3月：德国亥姆霍兹国家研究中心访问学者

2003年7月至今：浙江农林大学教师

教学工作

研究生课程：蛋白质工程，生物信息学，植物分子生物学专题，表观遗传学，细胞生物学

本科生课程：细胞与分子生物学，细胞生物学，分子生物学

科研项目

1.基于碳纳米管技术和转座子开发一种新型的、marker-free的植物转基因技术，浙江省自然科学基金重点项目，2024.1.1- 2026.12.31，主持

2.毛竹LTR反转录转座子响应环境变化的分子机理，国家自然科学基金项目，2019.1.1-2022.12.31，60万元，主持

3.毛竹MLE（mariner-like element）转座酶催化机理研究，浙江省自然科学基金重点项目，2019.1.1-2022.12.31，主持

4.毛竹LTR反转录转座子转座调控机理及对宿主生物多样性的影响，国家自然科学基金项目，2015.1.1-2018.12.31，87万元，主持

5.由居间分生组织调控的毛竹快速拔节生长的分子机理研究，国家自然科学基金项目，2016.1.1-2018.12.31，24万元，2/6

6.毛竹活性MITE的分离及与宿主基因表达调控网络互作机制解析，国家自然科学基金项目，2013.1.1-2016.12.31，80万元，主持

7.竹亚科LTR反转录转座子的分布和增殖模式及对宿主基因组进化的影响，浙江省杰出青年项目，2012.1.1-2016.12.31，30万元，主持

8.超活性mariner-like转座子的构建及在基因标签技术应用的探讨，国家自然科学基金项目，2010.1.1-2013.12.31，31万元，主持

论文与专著

1.论文：

1)Ding Y, Zou L, Ramakrishnan M, Chen Y, Zhu B, Yu L, &Zhou M. Abiotic stress-induced DNA methylation in transposable elements and their transcripts reveals a multi-layered response in Moso bamboo. Industrial Crops and Products.2024,210:118108

2)Hang T, Lin C, Asim M, Ramakrishnan M, Deng S, Yang P,Zhou M*. Low phosphorus impact on Moso bamboo (Phyllostachys edulis) root morphological polymorphism and expression pattern of the related genes. Tree Physiol. 2024,44(1):tpad138.

3)Ramakrishnan M, Papolu PK, Mullasseri S,Zhou M, Sharma A, Ahmad Z, Satheesh V, Kalendar R, Wei Q. The role of LTR retrotransposons in plant genetic engineering: how to control their transposition in the genome. Plant Cell Rep. 2023,42(1):3-15.

4)Lin C**, Hang T**, Jiang C, Yang P*,Zhou M*.Effects of different phosphorus levels on tiller bud development in hydroponicPhyllostachys edulisseedlings. Tree Physiol. 2023,43(8):1416-1431.

5)Wang Q, Yang P, Maharajan T, Ramakrishnan M, Asim M, Gui R*,Zhou M*. Strigolactone Mediates Moso Bamboo Root Response to Phosphate Stress. J Agric Food Chem. 2023,71(20):7921-7936.

6)Ramakrishnan M,Zhou M, Ceasar SA, Ali DJ, Maharajan T, Vinod KK, Sharma A, Ahmad Z, Wei Q*. Epigenetic modifications and miRNAs determine the transition of somatic cells into somatic embryos. Plant Cell Rep. 2023,42(12):1845-1873.

7)Zou L, Yang Y, Liu X, Ramakrishnan M, &Zhou M*.Comprehensive physiological, cytological, and transcriptional regulatory analyses reveal the coloration mechanism of culm yellow-slot mutation in moso bamboo (Phyllostachys edulis). Industrial Crops and Products.2023,204:117328

8)Yu L, Ding Y,Zhou M*.A long non-coding RNA PelncRNA1 is involved in Phyllostachys edulis response to UV-B stress. PeerJ. 2023,11:e15243.

9)Ramakrishnan M**, Papolu PK**, Satish L, Vinod KK, Wei Q, Sharma A, Emamverdian A, Zou LH,Zhou M*. Redox status of the plant cell determines epigenetic modifications under abiotic stress conditions and during developmental processes. J Adv Res. 2022, 42: 99-116.

10)Papolu PK**, Ramakrishnan M**, Mullasseri S, Kalendar R, Wei Q, Zou L−H, Ahmad Z, Vinod KK, Yang P andZhou M*. Retrotransposons: How the continuous evolutionary front shapes plant genomes for response to heat stress. Front. Plant Sci., 2022, 13:1064847.

11)Ramakrishnan M, Papolu PK, Mullasseri S,Zhou M, Sharma A, Ahmad Z, Satheesh V, Kalendar R, Wei Q. The role of LTR retrotransposons in plant genetic engineering: how to control their transposition in the genome. Plant Cell Rep. 2023,42(1):3-15.

12)Zhou X, Xie J, Xu C, Cao X, Zou L-H andZhou M*.Artificial optimization of bamboo Ppmar2 transposase and host factors effects on Ppmar2 transposition in yeast. Front. Plant Sci.2022,13:1004732.

13)Ding Y, Zou LH, Wu J, Ramakrishnan M, Gao Y, Zhao L,Zhou M*. The pattern of DNA methylation alteration, and its association with the expression changes of non-coding RNAs and mRNAs in Moso bamboo under abiotic stress. Plant Sci. 2022, 325:111451.

14)Ramakrishnan M, Rajan KS, Mullasseri S, Palakkal S, Kalpana K, Sharma A,Zhou M, Vinod KK, Ramasamy S, Wei Q. The plant epitranscriptome: revisiting pseudouridine and 2'-O-methyl RNA modifications. Plant Biotechnol J. 2022, 20(7):1241-1256.

15)Papolu PK, Ramakrishnan M, Wei Q, Vinod KK, Zou LH, Yrjala K, Kalendar R,Zhou M*. Long terminal repeats (LTR) and transcription factors regulatePHRE1andPHRE2activity in Moso bamboo under heat stress. BMC Plant Biol. 2021, 21(1):585.

16)Ramakrishnan, M., Satish, L., Sharma, A., Kurungara Vinod K., Emamverdian A.,Zhou M., Wei Q. Transposable elements in plants: Recent advancements, tools and prospects. Plant Mol Biol Rep.2022, 40: 628–645.

17)Ramakrishnan M, Satish L, Kalendar R, Narayanan M, Kandasamy S, Sharma A, Emamverdian A, Wei Q,Zhou M*. The Dynamism of Transposon Methylation for Plant Development and Stress Adaptation. Int J Mol Sci. 2021, 21;22(21):11387.

18)Ramakrishnan M, Yrjälä K, Sharma A, Satheesh V, Cho J,Zhou MB*. (2020). Genetics and genomics of moso bamboo (Phyllostachys edulis): current status, future challenges and biotechnological opportunities towards a sustainable bamboo industry. Food and Energy Security, Food Energy Secur. 2020, 9:e229.

19)Tao GY, RamakrishnanM,Vinod KK, Yrjälä K, Satheesh V, Cho J, Fu Y,Zhou MB*. Multi-omics analysis reveals cellular pathways for rapid growth of moso bamboo. Tree Physiology. 2020,40(11):1487-1508,.

20)Ramakrishnan M,Zhou M*, Pan C, Hänninen H, Yrjälä K, Vinod KK, Tang D. Affinities of Terminal Inverted Repeats to DNA Binding Domain of Transposase Affect the Transposition Activity of BambooPpmar2Mariner-Like Element. Int J Mol Sci. 2019, 20(15):3692

21)Li S**, Ramakrishnan M**, Vinod K K, Kalendar R, Yrjälä K, &Zhou M*. Development and deployment of high-throughput retrotransposon-based markers reveal genetic diversity and population structure of Asian bamboo. Forests. 2020, 11(1):31.

22)Ramakrishnan M,Zhou MB*, Pan CF, Hänninen H, Tang DQ, Vinod KK. Nuclear export signal (NES) of transposases affects the transposition activity of mariner-like elementsPpmar1andPpmar2of moso bamboo. Mob DNA. 2019, 10:35.

23)Zhou M*, Wu J, Ramakrishnan M, Meng X, Vinod K. Prospects for the study of genetic variation among Moso bamboo wild-type and variants through genome resequencing.Trees.2019, 33(2):371–381.

24)Zhou M*, Zhou Q,Hänninen H. The distribution of transposable elements (TEs) in the promoter regions of moso bamboo genes and its influence on downstream genes. Trees,2018.2(2):525–537.

25)Zhou M*, Zhu Y, Bai Y, Hänninen K, Meng X. Transcriptionally active LTR retroelement-related sequences and their relationship with small RNA in moso bamboo (Phyllostachys edulis). Molecular Breeding, 2017.37:132.

26)Zhou M*, Chen A, Zhou Q, Tang D, Hänninen K. A moso bamboo (Phyllostachys edulis) miniature inverted-repeat transposable element (MITE): the possible role of a suppressor. Tree Genetics & Genomes.2017,13: 129.

27)Zhou M, Hu H, Liu Z, Tang D. Two active bamboo mariner-like transposable elements (Ppmar1 and Ppmar2) identified as the transposon-based genetic tools for mutagenesis. Molecular Breeding.2016, 36:163.

28)Zhou M*, Liang L, Hänninen K. A transposition-activePhyllostachys edulisLTR retrotransposon. Journal of Plant Research.2018, 131:203–210.

29)Zhou MB, Hu H, Miskey C, Lazarow K, Ivics Z, Kunze R, Yang G, Izsvák Z, Tang DQ. Transposition of the bamboo Mariner-like element Ppmar1 in yeast. Mol Phylogenet Evol.2017,109: 367-374

30)Zhou M, Hu B, Zhu Y. Genome-wide characterization and evolution analysis of long terminal repeat retroelements in moso bamboo (Phyllostachys edulis). Tree Genetics & Genomes.2017, 13: 43.

31)Zhou M^*, Xu C, Shen L, Xiang W, Tang D. Evolution of genome sizes in Chinese Bambusoideae (Poaceae) in relation to karyotype. Trees.2017, 31(1): 41-48

32)Jiang KY,Zhou, MB*, Yang HY, Fang W. Cloning and functional characterization of PjCAO gene involved in chlorophyll b biosynthesis inPseudosasa japonicacv.Akebonosuji. Trees.2016, 30: 1303-1314

33)Zhou MB^*,Zheng Y, Liu ZG, Xia XW, Ding-Qin Tang DQ, Fu Y, Chen M. Endo-1,4-b-glucanase gene involved into the rapid elongation ofPhyllostachys heterocyclavar.pubescens.Trees.2016,30: 1259-1274

34)Zhou M^*, Tao G, Pi P, Zhu Y, Bai Y, Meng X. Genome-wide characterization and evolution analysis of miniature inverted-repeat transposable elements (MITEs) in moso bamboo (Phyllostachys heterocycla). Planta.2016, 244:775–787.

35)Jiang KY,Zhou MB^*. Cloning and functional characterization of PjPORB, a member of the POR gene family inPseudosasa japonicacv.Akebonosuji. Plant Growth Regulation.2016, 79(1): 95–106

36)An MM, Guo C, Lin PP,Zhou MB^*. Heterogeneous evolution of Ty3-gypsy retroelements among bamboo species. Genet. Mol. Res.,2016, 15(3).

37)Xia XW, Gui RY, Yang HY, Fu Y, Fang W,Zhou MB^*. Identification of genes involved in color variation of bamboo culms by suppression subtractive hybridization. Plant Physiology and Biochemistry.2015,97: 156-164

38)Zhou MB^*, An MM, Xia XW, Yang HY, Cheng MM, Wang KL, Fang W. Sequencing and phylogenetic analysis of the chloroplast genome ofPseudosasa japonicaf.Akebonosuji. Biochemical Systematics and Ecology.2016,69:41-50

39)Yang HY, Xia XW, Fang W, Fu Y, An MM,Zhou MB^*. Identification of genes involved in spontaneous leaf color variation inPseudosasa japonica. Genet MolRes,2015, 14 (4): 11827-11840

40)Zhou MB, Zhong H, Hu JL, Tang DQ.Ppmar1andPpmar2: the first two complete and intact full-length mariner-like elements isolated in Phyllostachys edulis. Acta Botanica Gallica: Botany Letters,2015, 162(2):127-137

41)Zhou MB, Liu XM, Tang DQ.PpPIF-1: first isolated full-lengthPIF-like element from the bambooPhyllostachys pubescens.Genet Mol Res.2012, 11 (2): 810-820

42)Zhou MB, Zhang Y, Tang DQ. Characterization and Primary Functional Analysis of BvCIGR, a Member of the GRAS Gene Family inBambusa ventricosa.Bot Rev.2011,77(3):233-242.

43)Zhou MB, Zhong H, Tang DQ. Isolation and characterization of seventy-nine full-length mariner-like transposases in the Bambusoideae subfamily. J Plant Res.2011, 124: 607–617

44)Zhou MB, Yang P, Gao PJ, Tang DQ. Identification of differentially expressed sequence tags in rapidly elongatingphyllostachys pubescensinternodes by suppressive subtractive hybridization. Plant Molecular Biology Reporter.2011, 29: 224-231

45)Zhou MB, Liu XM, Tang DQ. Transposable elements inPhyllostachys pubescens(Poaceae) genome survey sequences and the full-length cDNA sequences, and their association with simple-sequence repeats. Genet. Mol. Res.2011, 10 (4): 3026-3037

46)Zhou MB, Lu JJ, Zhong H, Liu XM, Tang DQ. Distribution and diversity of PIF-like transposable elements in the Bambusoideae subfamily. Plant Sci.2010, 179: 257-266.

47)Zhou MB, Lu JJ, Zhong H, Tang KX, Tang DQ. Distribution and polymorphism of mariner-like elements in the Bambusoideae subfamily. Plant Syst Evol.2010, 289: 1-11

48)Zhou MB, Zhong H, Zhang QH, Tang KX, Tang DQ. Diversity and evolution of Ty1-copia retroelements in representative tribes of Bambusoideae subfamily. Genetica.2010, 138: 861-868

49)Zhong H,Zhou MB^**, Xu CM, Tang DQ. Diversity and evolution of Pong-like elements in Bambusoideae subfamily. Biochem Syst Ecol.2010, 38: 750-758

50)Chen WW, Qin QP, Zheng YP, Wang C, Wang S,Zhou MB, Zhang C, Cui YY. Overexpression of Doritaenopsis Hybrid EARLY FLOWERING 4-like4 Gene, DhEFL4, Postpones Flowering in Transgenic Arabidopsis.2016, Plant Molecular Biology Reporter.34(1):103-117

51)Chen W, Qin Q, Zhang C, Zheng Y, Wang C,Zhou MB, Cui Y. DhEFL2, 3 and 4, the three EARLY FLOWERING4-like genes in a Doritaenopsis hybrid regulate floral transition. Plant Cell Rep.2015, 34(12): 2027-2041.

52)SunXS, Qin QP,ZhangJ, Zhang C,Zhou MB, Paek KY, Cui YY.Isolation and characterization of theFVEgene of aDoritaenopsishybrid involved in the regulation of flowering.Plant Growth Regulation.2012, 68(1): 77-78

53)SunXS, Qin QP,ZhangJ, Zhang C,Zhou MB, Paek KY, Cui YY.Cloning and characterization of aDoritaenopsishybridPRP39gene involved in flowering time.Plant Cell, Tissue and Organ Culture (PCTOC).2012, 110(3): 347-357

54)Qin QP, Kaas Q, Zhang C, Zhou LP, Luo XY,Zhou MB, Sun XM, Zhang LL, Paek KY, Cui YY. The Cold Awakening of Doritaenopsis ‘Tinny Tender’ Orchid Flowers: The Role of Leaves in Cold-induced Bud Dormancy Release. J Plant Growth Regul.2012, 31(2): 139-155

55)Luo XY, Zhang C, Sun XM, Qin QP,Zhou MB, Paek KY, Cui YY. Isolation and characterization of aDoritaenopsishybrid GIGANTEAgene, which possibly involved in inflorescence initiation at low temperatures.Kor. J. Hort Sci Technol.2011, 29 (2): 135-143

56)Dong WJ, Wu MD, Lin Y,Zhou MB, Tang DQ. Evaluation of 15 caespitose bamboo EST-SSR markers for cross-species/genera transferability and ability to identify interspecies hybrids. Plant Breeding.2011,130:596-600

57)Tang DQ, Lu JJ, Fang W, Zhang S,Zhou MB. Development, characterization and utilization of GenBank microsatellite markers inPhyllostachys pubescensand related species. Mol Breed.2010, 25: 299-311

58)Lin Y, Lu JJ, Wu MD,Zhou MB, Fang W, Ide Y, Tang DQ. Identification, cross-taxon transferability and application of full-length cDNA SSR markers inPhyllostachys pubescens. Springerplus.2014, 3:486.

联系方式

通讯地址：浙江省临安市武肃666号，浙江农林大学东湖校区智能实验楼S309室

邮 编：311300

电 话：13588152716

邮 箱：zhoumingbing@zafu.edu.cn